Article Review: Posttraumatic Stress Disorder in DSM-5: New Criteria and Controversies

As our knowledge of mental health issues continues to increase, The Diagnostic and Statistical Manual for Mental Disorders (DSM) must consistently update its analytic and disorder-specific criteria. It is essential to do so to ensure not only its relevance, but also its championing of the most current and accurate diagnostic information available. Each update or manual revision has the potential to create controversy or difficulties with implementation in practice. Miller, Wolfe and Keane (2014) recognized that the fifth and latest revision of the DSM (DSM-5) was no exception, especially with respect to the diagnosis of Posttraumatic Stress Disorder (PTSD). Additionally, new controversy has erupted related to the upcoming International Classification of Diseases, Edition 11 (ICD-11) (Miller, Wolf & Keane 2014).

 

Moving PTSD
Miller, Wolfe and Keane identified the removal of PTSD from the Anxiety Disorders chapter and into a new one titled “Trauma- and Stressor-related Disorders” as the most substantial and potentially controversial move made in the new revision. PTSD had previously been included with anxiety disorders, since its introduction in the DSM-III, even though some were apprehensive with the placement. The newly created chapter in the DSM-5, that now houses PTSD, was formulated to better reflect the heterogeneity of psychological distress found in samples of individuals exposed to serious adverse life events (Miller, Wolfe & Keane, 2014).

 

The researchers found that in the beginning, most developments related to PTSD came about because of its close association with anxiety disorders. They then noticed that as studies progressed, symptomology, as well as the backgrounds of those diagnosed with PTSD, revealed that re-experiencing the event was the key symptom. The majority of research they reviewed clearly identified fear and anxiety as being present and essential to varying degrees in the development of PTSD, but further noted that reliving the event was the principal complaint. (Miller, Wolfe & Keane, 2014).

 

The arguments against the move note that effective treatment for PTSD focuses on fear and anxiety. Therefore, many still believe that PTSD should be included under the meta-structured chapter of Anxiety Disorders. Our researchers disagree and explain that the DSM-5 even notes that anxiety and fear are more prominent for some patients than others, but are required symptomatology for all who are diagnosed with PTSD. (Miller, Wolfe & Keane, 2014).

 

Criterion A Changes
Miller et al (2014) listed several changes that were made to the definition of trauma (Criterion A). First, the types of involvements considered to be traumatic have been more specifically identified as sexual violence, serious injury or exposure actual or threatened death. “Exposure” can be in the form of direct contact, being a witness to the event, hearing about the event if it happened to those close to the person, and/or repeated exposure, such as what a trauma counselor would experience. The change in this information is to better clarify and differentiate from events that are life-altering but not traumatic.

 

A second change to Criterion A was the elimination of A2. It was a list of emotional responses that the person must have felt regarding the event. Study data revealed that the list was irrelevant to diagnosis because many persons do not experience those emotions at the time of the event. Therefore, since it was not purposeful to diagnosis, it was not needed as criteria for the disorder.

 

The third and final change to Criterion A was the wording of the language. With the change of traumatic “event” to “event(s)”, PTSD symptoms related to more than one trauma can now be diagnosed. It also made a diagnosis possible for those individuals who would not have met the criteria through one single event. Additionally, patients who have endured multiple traumas can include the events and symptoms as a collective instead of linking them to one isolated event.

 

Revision to the Specific Symptoms that Define PTSD
Miller et al. (2014) noted that adding three new symptoms to PTSD criteria, four symptom clusters instead of three, and adding a new diagnostic algorithm was the most palpable change. The first of the three new symptoms to be added was having “distorted cognitions about the cause or consequences of the traumatic event(s) that lead the individual to blame himself/herself or others.” The second is a “persistent emotional state.” Both of these symptoms can be found in Criterion D. The final symptom added to the DSM-5 was “reckless or self-destructive behavior” and it is in Criterion E. (DSM-5)

 

In mentioning the above symptoms, it is easy to note that Criterion E is the newly added symptom cluster. In addition to this cluster, the previous ones received modifications as well. Cluster B was only minimally effected with the change in wording from “re-experienced” to “intrusion.” Criterion C was aptly named “persistent avoidance of a stimuli associated with the traumatic event(s) and was derived from a combination from C1 and C2 from the previous DSM version. “Negative alterations in cognitions and mood that are associated with the traumatic event” was the term given to Criterion D. The new Criterion E was actually the hyperarousal cluster from the previous DSM-IV. It received a new title known as “alterations in arousal and reactivity that are associated with the traumatic event(s).” (Miller, Wolfe, & Keane, 2014).

 

The new diagnostic algorithm was one of the last changes noted by Miller et al. (2014). This algorithm indicates that to meet a PTSD diagnosis, an individual has to experience at least one symptom in both Criterions B and C as well as two symptoms in each Criterions D and E.

 

Initial Studies Examining the Impacts of these Changes
Miller et al. (2014) reviewed data from numerous empirical studies comparing and contrasting the occurrence of PTSD in the general population, veterans, college students and earthquake survivors. They found that in the initial studies that compared event exposure in the general population for prevalence estimates for a lifetime (L) and past six months (6M) were somewhat lower when defined in by the DSM-5 (L=8.3, 6M=3.8) when compared to the defined criteria in the DSM-IV (L=9.8, 6M=4.7). However, additional research and studies demonstrated that the DSM-5 was providing minutely higher approximations than the DSM-IV. Once study noted by our authors indicated that the when 185 volunteers were administered a revised version of the PTSD Scale, 50% met criteria for PTSD when assessed using the criteria in the DSM-IV and 52% met the criteria when using the DSM-5 (Calhoun, et al, 2012). The last study mentioned in the article utilized the college student population. It measured for students who would actually be clinically diagnosed with moderate functional impairment due to PTSD symptoms. Using the DSM-5 criteria, the prevalence estimate was 4.8% and 4.3% using the DSM-IV. Statistically, there was less than a one percent difference and deemed that DSM-5 had “no substantial” effect on prevalence when compared to the DSM-IV (Miller, Wolfe, & Keane, 2014).

 

Additionally, Miller et al. (2014) studied the configuration of factor loadings in the DSM-5 model. They found that the “amnesia” symptom and “new/reckless/self-destructive behavior” symptoms resulted in “weaker loadings on their respective factors in CFA (Miller, Wolfe & Keane, 2014). In further exploration, they identified a link between those who endorsed these symptoms and increased levels of PTSD.

 

Rater reliability was also analyzed. The findings were quite favorable. They suggested that even those professionals with moderate experience using the DSM-5 diagnostic criteria for PTSD were producing reliable diagnoses (Miller, Wolfe, & Keane, 2014).

 

The Dissociative Subtype of PTSD
A new dissociative subtype was added to the DSM-5 that included the features of derealization and/or depersonalization. The addition of this subtype is deemed controversial by some because there is still a debate of sorts as to whether or not the symptoms are basic features of PTSD or those that are experienced by a subset of individuals only. Miller et al. (2013) were the first to conduct a study utilizing latent profile analysis with the subtype and its correlation to PTSD.  Using CAPS (Blake et.al., 1995), they assessed a sample group of veterans and their partners. Three distinct groups emerged from their data: 1) low PSTD severity and no derealization/ depersonalization 2) high PTSD severity and no derealization/depersonalization 3) high PTSD severity (equal to group 2) and discernible symptoms of derealization and/or depersonalization. The third group is now titled as the dissociative subtype group (Miller, Wolfe, & Keane, 2014).

 

Patients who meet the criteria for the dissociative subtype experience more recurrent and forceful flashbacks, are more likely to have a history of sexual abuse, suffer psychogenic amnesia, psychiatric comorbidity, suicidal ideation and functional impairment (Miller, Wolfe, & Keane, 2014). Additionally, those linked with this subtype were found to experience an over-modulated reaction to trauma cues so much so that the frontal brain regions dynamically inhibit the limbic brain regions that are profoundly associated in emotional responsivity. Fear was found to be the emotion most responsible for this reaction (Lanius et al., 2012).  Miller et al. (2014) noted that the inclusion of this subtype into the DSM-5 provided a greater reliability in the conceptualization of dissociation across PTSD studies and diagnosis.

 

Conclusion
The diagnosis of PTSD continues to be surrounded by controversy. The new changes made in the DSM-5 have only worked to lengthen the debate for some. However, preliminary studies indicate that the modifications have not had a considerable effect on the approximations of PTSD prevalence. Likewise, the reliability of diagnosis using a clinical assessment has not experienced a significant effect due the changes, either.

 

References
Lanius, R. A., Brand, B., Vermetten, E., Frewen, P. A., & Spiegel, D. (2012). The dissociative subtype of posttraumatic stress disorder: Rationale, clinical and neurobiological evidence, and implications. Depression and Anxiety, 29, 701–708. doi:10.1002/da.21889

 

Miller, M., Wolf, E.J., & Keane, T. (2014). Posttraumatic Stress Disorder in DSM-5: New Criteria and Controversies. Clinical Psychology: Science and Practice, 21(N3), 208-220. doi:10.1111/cpsp.12070

 

Miller, M. W., Wolf, E. J., Kilpatrick, D., Resnick, H., Marx, B. P., Holowka, D. W., Friedman, M. J. (2013). The prevalence and latent structure of proposed DSM-5 posttraumatic stress disorder symptoms in U.S. national and veteran samples. Psychological Trauma: Theory, Research, Practice, and Policy, 5, 501–512. doi:10.1037/a0029730

 

Trauma and Stressor Related Disorders. (2013). In Diagnostic and statistical manual of mental disorders: DSM-5. (5th ed.). Washington, D.C.: American Psychiatric Association.

 

Crystal Bray, BS
WKPIC Doctoral Intern

Friday Factoid- Rising Mortality Rates for Middle-Aged White Americans

Case and Deaton (2015), both economists from Princeton, found that mortality rates for middle-aged white Americans have risen since 1999. In contrast, the death rate for middle-aged blacks and Hispanics continued to decline during the same period, as did death rates for younger and older people of all races and ethnic groups. They analyzed health and mortality data from the Centers for Disease Control and Prevention and other sources.

 

First, the authors ruled out an increase in deaths from chronic diseases such as heart disease, cancer, and diabetes. Those numbers were all either stable or trending downward. Murder and accidents were also declining. The authors concluded the rising annual death rates among this group are being driven by an epidemic of suicides. Most of the drug-related deaths in America are now caused by prescription medicines, and nearly three-quarters of those deaths are from opioid painkillers. Reliance on opioid painkillers is an epidemic that started in the late 1990s. Chronic liver diseases related to drug and alcohol use in this group were also on the rise.

 

Studies have found white patients with pain are more likely to be prescribed opioid painkillers. And whites have been more likely to attempt suicide when faced with physical or mental hardships. The New York Times reported 90 percent of people who tried heroin in the last decade were white. Drug addiction in black communities ultimately resulted in mass incarceration, while heroin and prescription drug abuse has been met with a more sympathetic approach, possibly because its victims are white. The only other time that death rates increased among middle-aged whites in the last century was in the 1960s because of smoking-related diseases. There was also a spike in mortality among younger adults in the 1980s during the AIDS epidemic.

 

One possible factor behind the substance abuse is this demographic group has faced a rise in economic insecurity over the past decade, driven by things like the financial crisis and the collapse of manufacturing. Education is also a factor. The effect was largely confined to people with a high school education or less. In that group, death rates rose by 22 percent while they actually fell for those with a college education. Mortality among the middle-aged population plummeted in the six other countries that the authors examined: Australia, Canada, France, Germany, United Kingdom, and Sweden. Although these countries also had economic problems in recent years, its residents might have been less affected because they have more social safety nets in terms of unemployment benefits and health care.

 

References:

 

Case, A. & Deaton, A. (2015) Rising morbidity and mortality in midlife among non-Hispanic Americans in the 21st century. Proceedings of the National Academy of Sciences. Retrieved from http://www.pnas.org/content/early/2015/10/29/1518393112.full.pdf

 

Gold, A. (2015, November 4). Why is death rate rising for white, middle-aged Americans? BBC News, Washington. Retrieved from http://www.bbc.com/news/world-us-canada-34714842

 

Kolata, G. (2015, November 2). Death Rates Rising for Middle-Aged White Americans, Study Finds. The New York Times. Retrieved from http://www.nytimes.com/2015/11/03/health/death-rates-rising-for-middle-aged-white-americans-study-finds.html

 

Storrs, C. (2015, November 4). Death rate on the rise for middle-aged white Americans. Retrieved from http://www.cnn.com/2015/11/03/health/death-rate-middle-age-white-americans/

 

 

Jonathan Torres, M.S.

WKPIC Doctoral Intern

Article Review: Impact of Person-Centered Planning and Collaborative Documentation on Treatment Adherence (Stanhope, Ingoglia, Schmelter, & Marcus, 2013)

Purpose
Mental health providers are faced with the challenges of completing quality documentation on time, building a therapeutic alliance, and managing a client’s treatment compliance. Stanhope, Ingoglia, Schmelter, and Marcus (2013) examined the impact of person-centered planning and collaborative documentation on service engagement and medication adherence within community mental health centers (CMHC). As part of person-centered planning, collaborative documentation is being explore as a tool that works to benefit the agencies and clients by ensuring treatment services appropriately reflect the client’s values and preferences and that documentation is completed in a timely manner.

 

Background
Stanhope, Ingoglia, Schmelter, and Marcus (2013) emphasized there are challenges clinicians experience with lack of engagement in mental health services among people with a mental illness. Contributing factors to disengagement from services include mistrust in the mental health system, poor alliances with providers, a perception that providers are not listening to them, and inadequate opportunities to make decisions and collaborate in treatment. Mental health agencies are starting to place an emphasis on transparency and utilizing a collaborative approach to documentation so that it represents a true reflection of the treatment session.

 

Historically, clinicians have viewed documentation as “the enemy” because it competes with time spent with clients and many rely on “no-show” appointments to complete paperwork. Collaborative documentation can be used as a clinical tool in completing assessments, treatment plans, and progress notes together with clients during the session. This method offers clients with the opportunity to share their input and perception on services that were provided. Additionally, it allows clients and clinicians to explore important issues, clarify any misunderstandings, and focus on progress.

 

According to the researchers, person-centered planning is defined as “a highly individual comprehensive approach to assessment and services.” This treatment approach allows providers to collaborate with clients to develop customized treatment plans that identify life goals and potential barriers. Person-centered care is a structured way of organizing treatment that focus on making continuous use of strengths-based assessment strategies, recognizing appropriate supports, and empowering clients to be active participants. During this study, researchers looked to determine whether person-centered care planning combined with collaborative documentation improved service engagement and medication adherence among clients at ten geographically diverse community mental health centers (CMHCs).

 

 

Methodology
This study was a randomized controlled trial of person-centered care planning with collaborative documentation among clients receiving services at ten CMHCs. Five CMHCs were randomly assigned to the experimental condition, which provided training in person-centered planning and collaborative documentation to agency clinicians. The five CMHCs in the control condition provided treatment as usual. The study period was 11 months (May 2009 to March 2010).

 

For clients to be eligible for this study, participants were required to be aged 18 or older, have had one or more psychiatric hospitalizations or two or more psychiatric emergency room visits in the past year, have a DSM-IV axis I diagnosis, and meet at least two functional criteria of severe mental illness. Altogether, 177 clients at the CMHCs in the experimental condition and 190 clients at the CMHCs in the control condition participated.

 

The first aim of this study was to compare changes in the overall rate of clinician-reported medication adherence between clients in the experimental CMHCs and clients in the CMHCs in the control group. The provider who was best able to determine a client’s medication adherence rated adherence (yes or no) on a monthly basis for 11 months. For the second aim, client-level analyses were conducted separately for CMHCs in the experimental and control groups to examine whether the odds of medication adherence changed over time. Finally, logistic regression models, including a random effect for site, were run to calculate the effect of the intervention on the odds of an appointment no-show. The models used data received from each CMHC on the total number of appointment no-shows and the total number of appointments.

 

Conclusion
Results indicate the intervention had a positive impact on medication adherence over time. Medication adherence at CMHCs in the experimental condition increased by 2% per month over the 11-month period (B=.022, p≤.01). The control condition showed no significant change in rate of medication adherence (B=.004, p=.25), and by the end of the study, the rate of medication adherence for the control condition was lower than for the experimental condition.

 

In the client-level analyses, the odds of medication adherence over 11 months increased by 25% among clients in the experimental condition but by only 1% among clients in the control condition. An intervention effect generally was seen across client-level characteristics. Medication adherence over the 11-month study among clients with schizophrenia and bipolar disorders was significantly more improved at CMHCs in the experimental group.

 

Overall, the study found that person-centered planning and collaborative documentation were associated with greater engagement in services (a decrease in no-shows) and higher rates of medication adherence. Therefore, the study findings supported the theory that if clients have greater control over their treatment and services are genuinely oriented toward their individual goals, clients will be more engaged with services and more compliant with medication.

 

 

References
Stanhope, V., Ingoglia, C., Schmelter, B., & Marcus, S. (2013). Impact of Person-Centered Planning and Collaborative Documentation on Treatment Adherence

Psychiatric Services, 64 (1), 76–79.

 

 

Jonathan Torres, M.S.

WKPIC Doctoral Intern

Friday Factoids: Promising Long-Term Treatment for PTSD

 

Post-traumatic stress disorder (PTSD) can result from being the victim or witness to a number of traumatic events including war, an automobile accident, physical abuse, assault, homicide, and other difficult or devastating experiences. It is an equal opportunity disorder and affects men, women, and people of all cultures similarly. In the United States, PTSD has been thrown into the limelight due to the number of service men and women who are returning from active duty with this condition. The current publicity around PTSD has left many in the medical and mental health fields looking to and for variations of treatment in hopes of finding more effective, longer-lasting methods to treat this illness.

 

One of the more promising treatments, currently in Phase 2 of 3 in testing, is MDMA-Assisted Psychotherapy. MDMA (3,4-methylenedioxymethamphetamine) is a psychedelic, synthetic substance noted for its capability to help patients delve into their excruciating memories. The drug reportedly facilitates trust and compassion between the patient and therapist, all the while greatly reducing the patient’s feelings of defensiveness and terror while in session. It is believed that MDMA is able to offer this therapeutic safe haven by stimulating the release of hormones (prolactin and oxytocin) linked to bonding and trust which comforts the patient and reduces symptoms of avoidance and panic.

 

According to the research data, an astounding 83% of participants who received the treatment no longer met the guidelines for PTSD while in Phase 2 of the study.  Additionally, many of those participants reported the results lasted 3 ½ years or longer. So, why is this treatment not already approved and readily available for those who so desperately need it?

 

One potential answer to that question could be the stigma surrounding MDMA.  Most all of you have heard it referred by it street names of “Molly” or  “ecstasy.” And given so, some will not be comfortable using it as an aid during therapy even in a controlled setting providing such positive, long-term results. Secondly, the cost and time frame for each individual trial is fairly massive.  The End of Stage 2 meeting is estimated to take an additional 3 years and $2.3 million before presenting results to the FDA. Afterwards, Stage 3 is speculated to have a price tag of $15.8 million and spanning 5 years until the treatment is fully available for use with the public.

 

References
MDMA-Assisted Psychotherapy. (n.d.). Retrieved September 9, 2015, from http://www.maps.org/research/mdma

 

Treating PTSD with MDMA-Assisted Psychotherapy – Home. (n.d.). Retrieved September 8, 2015, from http://www.mdmaptsd.org/index.html

 

Crystal K. Bray, B.S.
WKPIC Doctoral Intern

Friday Factoids Catch-Up: Is Stress Contagious?

Research is demonstrating that stress can be contagious across various populations. In a study completed by Waters, West, and Mendes (2014) results indicate that babies quickly pick up their mother’s stress and show corresponding physiological (cardiac) changes. West et al. (2014) findings demonstrate that emotions may be communicated through a variety of channels, such as odor, vocal tension, facial expression, or touch.  This leads to questions of whether these findings are applicable to adults or among strangers? Can stress still be contagious beyond the intimate bond of mother and child?

 

Findings from Engert, Plessow, Miller, Kirschbaum, and Singer (2014) show that observing others in a stressful situation can make your body release the stress hormone cortisol.   The results show that being around a loved one or a stranger that is stressed results in quantifiable stress reactions.  This study involved having subjects paired with loved ones and strangers of the opposite sex, and then divided participants into two groups.  One group underwent challenging math questions and an interview to emulate a stressful situation, whereas the other group of 211 participants observed the test.  Only 5% of the participants that were involved in the stressful situation remained calm, while the other 95% showed signs of stress. Interestingly, 26% of observers had increased cortisol indicating empathetic stress.  When directly observed, empathetic stressed increased significantly when the observer watched a loved-one experience stress.  Additionally, empathetic stress increased when observers watched a stranger in a stressful situation via video transmission.

 

Overall, stress is a major health threat in today’s society; even still, the likelihood of coming into contact with stressed individuals is also prominent (Max-Planck-Gesellschaft, 2014).  Thus understanding the impact of stress and empathetic stress is important for developing prevention and/or intervention strategies.   As Engert et al. (2014) suggest, we should be cautious of watching or observing stressful shows or other stimuli, as this may transmit stress to the viewers (Max-Planck-Gesellschaft, 2014).  Also, the results of the study show that emotional closeness is a facilitator but not necessary to the experience of empathetic stress.  Respective of these studies, the authors conclude “stress has enormous contagion potential” (Max-Planck-Gesellschaft, 2014).

 

References
Engert, V., Plessow, F., Miller, R., Kirschbaum, C., & Singer, T. (2014). Cortisol Increase in empathic stress is modulated by social closeness and observation modality. Psychoneuroendocrinology, 45, 192-201. DOI: 10.1016/j.psyneuen.2014.04.005

 

Waters, S. F., West, T. V., & Mendes, W. B. (2014).  Stress contagion: Physiological covariation between mothers and infants. Psychological Science, 25(4), 934-942. doi:  10.1177/0956797613518352

 

Max-Planck-Gesellschaft. (2014).  Your stress is my stress. Retrieved from http://www.mpg.de/research/stress-empathy

 

Dannie S. Harris, M.A., M.A., M.A.Ed., Ed.S.
WKPIC Practicum Trainee